Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 AlteredExpression phenotype LHGDN Factor V Leiden causing activated protein C resistance is the most common inherited form of thrombophilia leading to thrombosis. 17456626 2007
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors. 15691154 2004
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis. 14695241 2004
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype LHGDN ABO blood group genotypes and the risk of venous thrombosis: effect of factor V Leiden. 15634288 2005
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN These data suggested that the factor V Leiden mutation might be a risk factor for the development of thrombosis in Behcet's disease patients. 12632020 2003
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype LHGDN The roles of factor V Hong Kong (FV Hong Kong), factor V Leiden (FV Leiden), factor II G20210A (FII G20210A), methylenetetrahydrofolate reductase (MTHFR) C677T, and MTHFR A1298C mutations in Turkish patients with thrombosis (270 patients) compared with healthy controls (114 subjects) were evaluated. 17911197 2007
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN The G20210A prothrombin gene, factor V Leiden, and MTHFR C677T mutations have been identified as predisposing genetic factors for thrombosis. 15958894 2005
Entrez Id: 5624
Gene Symbol: PROC
PROC 		0.340 GeneticVariation phenotype LHGDN The data from this model predict an increased risk of perioperative thrombosis due to inhibition of APC function in cardiac surgical patients heterozygous for the F5L mutation. 11761087 2001
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 GeneticVariation phenotype LHGDN The 4G allele is associated with higher levels of PAI-1, and might increase the risk for intravascular thrombosis. 17949795 2008
Entrez Id: 5624
Gene Symbol: PROC
PROC 		0.340 Biomarker phenotype LHGDN In uremia, plasma levels of anti-protein C and anti-protein S antibodies are associated with thrombosis. 16105054 2005
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 GeneticVariation phenotype LHGDN Among the eight PTFEG patients with thrombosis, seven were PAI 4G/5G. 18609532 2008
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN Control of von Willebrand factor multimer size and implications for disease. 12163004 2002
Entrez Id: 2152
Gene Symbol: F3
F3 		0.340 Biomarker phenotype LHGDN This review focuses on the roles of TF in hemostasis, thrombosis, and vascular development. 15117736 2004
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN von Willebrand factor: two sides of a coin. 16102036 2005
Entrez Id: 2152
Gene Symbol: F3
F3 		0.340 Biomarker phenotype LHGDN Tissue factor: in at the start...and the finish? 12871349 2003
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN Functional property of von Willebrand factor under flowing blood. 11843285 2002
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN In this study we hypothesized that anthrax infection modulates the activity of von Willebrand factor (VWF) and its endogenous regulator ADAMTS13, which play important roles in hemostasis and thrombosis, including interaction of endothelial cells with platelets. 18263586 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 GeneticVariation phenotype LHGDN PAI-1 gene 4G/5G genotype: A risk factor for thrombosis in vessels of internal organs. 12353306 2002
Entrez Id: 5624
Gene Symbol: PROC
PROC 		0.340 GeneticVariation phenotype LHGDN Factor V Leiden, prothrombin G20210A, and protein C mutation frequency in Turkish venous thrombosis patients. 18160601 2008
Entrez Id: 2152
Gene Symbol: F3
F3 		0.340 AlteredExpression phenotype LHGDN Tissue factor expression induced by local inflammation is involved in the pathogenesis of thrombosis in patients with nonvalvular atrial fibrillation. 14678810 2003
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 Biomarker phenotype LHGDN The data collected from this population-based study demonstrate significant sex differences in PAI-1 and critical factors that may influence risk of thrombosis. 17985503 2007
Entrez Id: 2152
Gene Symbol: F3
F3 		0.340 AlteredExpression phenotype LHGDN Elevated TF and TFPI levels may be related to thrombosis and atherosclerosis in CRF patients on PD. 14610342 2003
Entrez Id: 5624
Gene Symbol: PROC
PROC 		0.340 GeneticVariation phenotype LHGDN These data indicate that individuals carrying the 4600AG genotype have high sEPCR levels but do not have an increased risk of thrombosis, whereas individuals carrying the 4678CC genotype have higher APC levels and lower risk of venous thromboembolism. 15116250 2004
Entrez Id: 10544
Gene Symbol: PROCR
PROCR 		0.330 GeneticVariation phenotype LHGDN This review highlights the different mutations/polymorphisms reported in the EPCR gene and their association with the risk of thrombosis. 17849044 2007
Entrez Id: 10544
Gene Symbol: PROCR
PROCR 		0.330 GeneticVariation phenotype LHGDN Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. 15116250 2004